X-linked lymphoproliferative disease (XLP) is a primary immunodeficiency caused by mutations in SH2D1A which encodes SAP.SAP functions in signalling pathways elicited by the SLAM family of leukocyte receptors.A defining feature of XLP is exquisite sensitivity to infection with EBV, a B-lymphotropic virus, but not other viruses.Although previous stu
Recently, the putative association between selective serotonin reuptake inhibitor (SSRI) exposure during pregnancy and the development of social disorders in children has gained increased attention.However, clinical studies struggle with the confounding effects of maternal depression typically co-occurring with antidepressant treatment.Furthermore,
With increasing the security treat and terrorisms that involving the use of firearm and to optimize the security thenmaximum PREPARE protection for he safety of the security guards, armies, and polices should be put in consideration.In order toconduct their duties properly and to protect their safety, the security guard should be completed with bul
Membrane proteins are broadly classified as transmembrane (TM) or peripheral, with functions that pertain to only a single bilayer at a given time.Here, we explicate a class of proteins that contain both transmembrane and peripheral domains, which we dub transmembrane membrane readers (TMMRs).Their transmembrane and peripheral elements anchor them
Nasogastric tube syndrome (NGTS) induced by a nasointestinal ileus tube is an uncommon but potentially life-threatening complication.NGTS often becomes serious and progresses to acute upper airway obstruction caused by bilateral vocal cord paralysis or laryngeal infection.Early detection and proper treatment of NGTS are necessary.We describe the PR